In your 20s, your skin was radiant, your energy seemed endless, and you felt unstoppable.
By your 30s, you noticed fine lines and a slight loss of elasticity. But as you enter your 40s and 50s your skin loses its youthful glow, becoming saggy with fine lines and wrinkles.
You might have also noticed that some people age faster than others some people have that youthful glow even in later age. This is not just getting older there is a hidden factor that most people ignore.
You might think that getting wrinkles and losing your youthful glow is just part of getting older.
However, groundbreaking research by Harvard's Professor David Sinclair reveals a different story. He explains that accelerated aging is due to cellular changes, where our cells begin to "forget" their usual functions as we age.
As we get older, our body's ability to neutralize oxidative stress, free radicals, and inflammation diminishes. This reduced ability, combined with external factors like pollution and toxins, impairs our cellular repair mechanisms.
As a result, our cells can no longer perform at optimal levels like they did when we were younger.
This leads to various age-related problems such as frequent fatigue, poor metabolism, and loss of mental clarity. Our skin cells are particularly affected, resulting in fine lines, wrinkles, and a loss of youthfulness and elasticity.
Sinclair's key observation highlights the decline of a specific molecule called NAD+ as central to this process. NAD+ is crucial for cellular repair and protection. As NAD+ levels drop, our cells lose their ability to repair themselves and fend off damage, accelerating aging in our 40s and 50s.
This decline leads to wrinkles, fine lines, a loss of youthful glow, and other age-related issues like fatigue and cognitive decline.
NAD (Nicotinamide Adenine Dinucleotide) is known as the "Molecule of Youth." It’s essential for converting food into energy, repairing damaged DNA, and keeping cells healthy.
NAD helps protect our cells from damage caused by oxidative stress, free radicals, and inflammation, which are key factors in skin aging.
In our 20s, we have plenty of NAD+. This high level helps neutralize free radicals and fight oxidative stress, keeping our body, skin, and cells in top condition.
That's why our skin looks so youthful and vibrant. As we get older, NAD+ levels naturally drop, affecting our skin and overall health.
With less NAD+, our skin cells lose energy and regenerative ability, making it harder to repair damage. This leads to wrinkles, fine lines, and dull, tired-looking skin. Our skin also becomes less capable of fighting oxidative stress, resulting in more damage from UV rays and pollution, making it less elastic, less hydrated, and more aged-looking.
In 3 months, you wake up feeling refreshed and full of energy. As you glance in the mirror, your skin looks radiant and smooth, with fine lines noticeably diminished.
Throughout the day, you receive compliments on your youthful glow and vibrant energy. Friends and strangers ask, “What’s your secret?” At work, you experience newfound sharpness, easily tackling tasks and impressing everyone. You become the center of attention for your radiant skin and positive outlook.
At home, you have the energy to pursue hobbies, start a new fitness routine, or spend quality time with loved ones.
Traditional anti-aging solutions like vitamins, creams, and collagen supplements only offer temporary fixes. Invasive treatments like Botox and fillers can be risky.
The real solution is boosting your NAD+ levels, which slows the aging process from the inside out.
All this isn't just about looking younger. It's about feeling more energetic, vibrant, and youthful. It's about taking care of the person who matters most, YOU.
Imagine looking in the mirror and seeing a person who looks many years younger. In 3 months, you smile and think, "Wow, this really works!" Why not give yourself the chance to relive this vibrant and youthful life again?
Boosting NAD+ levels is crucial for reversing many aspects of aging, rejuvenating cells, and enhancing overall health.
The challenge is that NAD+ isn't stable with heat and can break down in your stomach, making pills and supplements ineffective.
The best way to increase NAD+ is by taking NMN (Nicotinamide Mononucleotide), a compound naturally found in all life forms. NMN supplementation has been shown to boost NAD+ levels effectively and for longer periods.
NMN is safe because it’s already present in our bodies and some foods we eat, so our system knows how to handle it well.
Once you manage your NMN levels, your NAD+ levels will stay high as you age. When your NAD+ levels are optimal, your body can naturally manage and reverse many signs of aging.
At HumaSpan, our mission is to significantly enhance the quality of life through the latest research.
As the founders, we delved deep into aging research and collaborated with top experts.
After extensive research and testing, we developed NADrive, the purest and most potent NMN supplement (1000mg). It’s third-party tested and contains a powerful blend of three ingredients...
One challenge with NMN is its bioavailability and absorption. Even in the right quantity, our body can't absorb it completely. To address this, we added Bioperine to enhance absorption. We also included Betaine Anhydrous, which hydrates cells, improves metabolic function, and boosts energy.
Studies suggest NMN supplementation can increase NAD+ levels in the body, potentially improving energy, metabolism and promoting cell repair
NMN shows promise in pre-clinical studies for various health benefits, particularly related to aging and age-related diseases
Betaine anhydrous shows potential for some health benefits, particularly related to homocysteine metabolism and liver health
Black pepper fruit extract (Bioperine) shows promise in enhancing nutrient absorption, offering potential benefits for overall health
If you have any questions or doubts, please feel free to contact our founders and experts at hello@humaspan.com. We'll respond within 24 hours.
By boosting NAD+ levels, NMN may help reverse some aging signs and improve cellular functions, potentially extending lifespan.
NMN is a precursor to NAD+, which is crucial for energy metabolism in cells. Higher NAD+ levels support enhanced energy production, which is vital for aging cells.
By promoting creatine synthesis and reducing fatigue, betaine may improve muscle performance and endurance, beneficial for aging adults to maintain physical activity levels.
Betaine may reduce oxidative stress and inflammation in the body, contributing to reduced aging signs and lower risk of chronic diseases.
NMN significantly elevates NAD+ levels, which is essential for cellular energy, DNA repair, and regulating the aging process. Neutralizing free radicals mitigates oxidative stress, enhancing cellular health and promoting longevity.
Betaine boosts energy and slows metabolic aging by supporting mitochondrial function and serving as a cellular hydrator. It also fights free radicals, prevents cell dehydration, and enhances nutrient absorption, crucial for overall health.
Bioperine improves the bioavailability and absorption of essential vitamins and minerals. Its antioxidant capabilities combat oxidative stress, supporting efforts against aging.
Disclaimer: We are not endorsed or affiliated by Harvard, David Sinclair, NIH, WebMD, any of the articles, publications, or individuals mentioned on this website.
If you have any questions or doubts, please feel free to contact our founders and experts at hello@humaspan.com. We'll respond within 24 hours.
NAD+ is a coenzyme that plays a vital role in cellular functions, and can be found in every cell in the body. It has two primary functions; converting nutrients into energy, and regulating metabolic processes. Acting as an electron transporter, NAD+ facilitates various reactions and processes within our cells, working in tandem with NADH. It also regulates our sleep/wake cycle, or circadian rhythm.
NAD+ enables other molecules to perform their functions effectively, but as we age, levels of NAD+ decrease. This hinders the activities of various NAD (H) dependent enzymes in oxidative phosphorylation, TCA cycle, and glycolysis, resulting in lower ATP production. Additionally, it can affect levels of PARP and sirtuins, leading to the inactivation of certain downstream molecular pathways that play a role in DNA repair.
In other words, NAD+ is crucial for the proper functioning of the body, and its depletion can lead to a slower metabolic rate and less effective self-repair. Without NAD+, our cells will generate less energy, making it difficult for the body to carry out its functions. Therefore, the importance of NAD+ lies in its ability to help other beneficial molecules perform their jobs.
Exploring NMN and NAD+ for Mitigating Aging-Related Dysfunctions
Nicotinamide Mononucleotide (NMN) is the precursor of NAD+ that is naturally converted by the body into NAD+. NMN is more stable than NAD+ and increasing NMN levels has been shown to enhance NAD+ biosynthesis, which can help combat age-related dysfunctions.
Taking NMN is the optimal approach to increase NAD+ levels. NMN is more stable than NAD+ and can stably boost NAD+ pools for a longer duration. Increasing NMN has all the benefits of NAD+ and specifically helps with vision and hearing loss related to aging. Additionally, it promotes sirtuin genes, which activate longevity and anti-aging mechanisms.
There are only a few reliable suppliers of enzymatically produced NMN. Good quality NMN is highly-priced. One of the key things to look out for when choosing an NMN supplement is to choose 99.9% pharmaceutical-grade NMN from a reliable source. Another important factor in efficacy is proper dosing. In order for NMN or any supplement to be effective it must be properly dosed. There are plenty of underdosed supplements on the market. Infinium, NADrive and VitaSpan are meticulously dosed and formulated for optimal results.
Chronological age refers to the number of years you've been alive, while biological age is calculated based on physiological evidence of how old your cells and tissues are. Even if you are of a certain age, being healthy and fit can give you a lower biological age. On the other hand, if you lead a sedentary lifestyle or have chronic illnesses, your biological age may be higher than your chronological age. While chronological age is static and unchangeable, biological age can be influenced by lifestyle choices and supplementation.
Although there have been no human studies that specifically determine at what age one should start taking NAD+ supplements, current research recommends starting NAD+ supplementation around midlife, which could be as early as 30 years of age.
Taking NMN supplements daily can result in visible changes within two to three weeks, including increased energy and awareness. While the supplement starts working within fifteen minutes, the full benefits may not be physically noticeable until the two to three week mark. After consistent use, notable differences in both internal and external health may be observed.
You’ll immediately start to feel some of the short term benefits of NMN supplements within your first couple uses and they can consist of higher energy levels and also a greater awareness. After a few weeks of use, you should start to see some notable differences in how you look and feel, both internally and externally.
With the addition of NMN supplements to your daily routine, you may quickly feel a difference in your energy levels and metabolism. You may experience increased energy throughout the day and find it easier to remain active. This is the first indication that NMN is starting to work.
NMN requires time to activate its effects. It takes roughly three weeks for your body to acclimate to the supplement and begin absorbing the NMN molecules.
Around the 3-4 month mark, you should start to feel more profound effects. You will experience sustained and youthful energy, deeper and more restful sleep, and increased ability to focus. Additionally, some people will find it easier to recover from muscle soreness and bearable aching joints.