Harvard Scientists Uncover the Hidden Root Cause of Accelerated Aging and Age-Related Issues Like Fatigue, Brain Fog, and Poor Sleep

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Groundbreaking research from Harvard has revealed a long-overlooked deficiency in the body that accelerates aging and drains youthful vitality.

This breakthrough explains why so many people experience a noticeable decline in energy, mental clarity, and physical resilience as they age.

In your 20s, you were unstoppable—full of energy, radiance, and an undeniable zest for life.

But as time passed and you entered your late 30s, 40s, and beyond, things began to change.

Life became more demanding and more stressful.

Now, you find yourself juggling a career, raising a family, and trying to keep up with social connections. As each day passes, the responsibilities at work, home, and your personal life seem to multiply, demanding more energy and resilience than you ever imagined.

As the years go by, your body isn't what it once was.

You begin to notice a decline in stamina, your mental clarity slowly fades, and restless nights with poor sleep become increasingly common.

This dip in physical resilience starts to make it increasingly difficult to face daily challenges head-on.

It's easy to believe that this decline is just a natural part of aging—just getting old. Or maybe you think medication or a better diet alone will fix it. To get through the day, you may have turned to quick fixes—caffeine, energy drinks, and stimulants.

Then, at night, you rely on medications to unwind and fall asleep. At first, these temporary solutions seem like lifelines, but they often come with side effects, creating a cycle of dependency that further drains your vitality.

But what if the real issue lies deeper within your body, something that's been overlooked?

Groundbreaking research from Harvard has revealed a long-overlooked deficiency in the body that accelerates aging and drains youthful vitality.

This breakthrough explains why so many people experience a noticeable decline in energy, mental clarity, and physical resilience as they age.

In your 20s, you were unstoppable—full of energy, radiance, and an undeniable zest for life.

But as time passed and you entered your late 30s, 40s, and beyond, things began to change. Life became more demanding and more stressful.

Now, you find yourself juggling a career, raising a family, and trying to keep up with social connections.

As each day passes, the responsibilities at work, home, and your personal life seem to multiply, demanding more energy and resilience than you ever imagined.

As the years go by, your body isn't what it once was.

You begin to notice a decline in stamina, your mental clarity slowly fades, and restless nights with poor sleep become increasingly common.

This dip in physical resilience starts to make it increasingly difficult to face daily challenges head-on.

It's easy to believe that this decline is just a natural part of aging—just getting old. Or maybe you think medication or a better diet alone will fix it.

To get through the day, you may have turned to quick fixes—caffeine, energy drinks, and stimulants. Then, at night, you might rely on medications to unwind and fall asleep.

At first, these temporary solutions seem like lifelines, but they often come with side effects, creating a cycle of dependency that further drains your vitality.

But what if the real issue lies deeper within your body, something that's been overlooked?

Recently, groundbreaking research from a Harvard University professor David Sinclair in longevity and healthy aging revealed a startling discovery: a 'youth molecule' within our bodies that gradually diminishes with age.

As the deficiency of this molecule increases with age, it disrupts cellular repair and energy production, leading to fatigue, a loss of youthful vitality, and accelerated aging.

As soon as you replenish this deficiency, you'll restore the molecule to the levels you had in your 20s, reviving your youthful energy, mental clarity, better sleep, and glowing skin.

As the deficiency of this molecule increases with age, it disrupts cellular repair and energy production, leading to fatigue, a loss of youthful vitality, and accelerated aging.

As soon as you replenish this deficiency, you'll restore the molecule to the levels you had in your 20s, reviving your youthful energy, mental clarity, better sleep, and glowing skin.

In the past, this information was exclusive to celebrities and the wealthy. But now, thanks to this Harvard breakthrough, thousands of people are already replenishing this deficiency, reclaiming their youthful vitality, and witnessing remarkable transformations.

Here's What Harvard Researchers and Doctors Have Revealed…

Groundbreaking research by Harvard's Professor David Sinclair has uncovered a critical molecule in our body that plays a vital role in maintaining youthfulness and energy—it's called NAD+.

In your 20s, NAD+ levels were at their peak, enabling your body to convert food into energy, repair damaged DNA, and keep your cells healthy.

These high levels also helped neutralize oxidative stress, free radicals, and inflammation—key factors that contribute to aging.

But as the years go by, your body becomes increasingly deficient in NAD+, and its levels begin to drop sharply, plummeting by 50% to 90%.

Groundbreaking research by Harvard's Professor David Sinclair has uncovered a critical molecule in our body that plays a vital role in maintaining youthfulness and energy—it's called NAD+.

In your 20s, NAD+ levels were at their peak, enabling your body to convert food into energy, repair damaged DNA, and keep your cells healthy.

These high levels also helped neutralize oxidative stress, free radicals, and inflammation—key factors that contribute to aging. But as the years go by, your body becomes increasingly deficient in NAD+, and its levels begin to drop sharply, plummeting by 50% to 90%.

Symptoms & Impact of NAD+ Deficiency

20-29 years

High energy & vitality
Vibrant enthusiasm for life
Sharp mental clarity & excellent focus
Strong metabolism
High immunity
Good sleep quality
Youthful skin appearance

30-39 years

Decrease in energy & vitality
Less enthusiasm for life
Occasional fatigue
Minor decline in mental clarity & focus
Slower metabolism
Weakened immune response
Sleep disturbances
Initial signs of skin aging

40-49 years

Persistent fatigue
Reduced mental clarity & focus
Consistent brain fog
Slower metabolism
Potential weight gain
Frequent illnesses
Poor sleep quality
Noticeable signs of skin aging

50-59 years

Chronic fatigue
Significant brain fog
Reduced focus
Weight gain due to slower metabolism
Frequent colds and infections,
Poor sleep quality
More pronounced skin aging

60-69 years

Severe energy decline
Cognitive issues
Severe brain fog
Gut health issues
Slow metabolism
Frequent illnesses
Poor sleep quality
Skin aging

70-79 years

Extreme fatigue
possible cognitive decline
Gut health problems
High susceptibility to infections
Very poor sleep quality
Overall frailty

How Boosting NAD+ Levels Slows Aging by Activating ‘Longevity Genes,’ Restores Vitality, Clears Brain Fog, and Improves Sleep...

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As NAD+ levels rise, your body efficiently converts nutrients into energy, fueling every cell.
NAD+ powers your cells, restoring energy production to youthful levels, similar to your 20s.
This energy surge boosts overall vitality, making you feel more alert and ready for daily challenges.

With more NAD+, your body activates sirtuins—genes that repair cellular damage and reduce inflammation.
Sirtuins work to preserve cells, protecting them from aging and wear.
This gene activation keeps your cells youthful, enhancing longevity and resilience.

As NAD+ increases, your body becomes more effective at repairing and regenerating cells.
This improved repair process replaces damaged cells with healthy ones, rejuvenating skin and fighting aging.
Over time, these improvements lead to more youthful skin and enhanced vitality.

With increased NAD+, brain cells receive more energy, sharpening cognitive function.
This boost in energy clears brain fog and enhances focus and concentration.
Your mental clarity returns, improving productivity and decision-making.

NAD+ helps regulate circadian rhythms, improving your natural sleep-wake cycle.
This leads to deeper sleep, allowing your body to recover and recharge more effectively.
You wake up refreshed, with higher energy levels and renewed vitality.

As NAD+ boosts cellular energy, your immune system strengthens, becoming more effective at fighting illness.
A more robust immune system leads to faster recovery and greater protection against infections.
With enhanced immunity, your body stays healthier and more resilient to aging-related challenges.

With NAD+ levels stable, your body consistently produces energy, maintaining stamina and vitality.
This sustained energy keeps you feeling youthful and active, similar to how you felt in your younger years.
Your body continues to thrive with sharper focus, greater energy, and better health as you age.

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What if You Could Meet The Younger You in Just 3 Months?

Three months from now, you wake up feeling refreshed and full of energy. Your skin has transformed, glowing with youthfulness, and those wrinkles have visibly softened.

Your eyes sparkle, and you can hardly believe the transformation.

As you move through your day, compliments start pouring in—people notice your vibrant energy and youthful appearance. Friends and even strangers ask, "What's your secret?" At work, you handle tasks with a new level of sharpness, impressing everyone with your clear focus.

Soon enough, you become the center of attention for your positive outlook and increased productivity. By the time you’re home, you have the energy to pursue hobbies, start a new fitness routine, or spend quality time with loved ones. Your metabolism feels revitalized, effortlessly helping you manage your weight.

You notice your immune system is stronger, illnesses ease, and you recover quickly from any ailments. In the past, you might have relied on traditional anti-aging solutions—vitamins, immunity supplements, creams, and collagen products—but they only offered temporary fixes, masking the symptoms without addressing the root causes of aging.

Now, you understand that the real solution lies in boosting the essential compounds you had in your youth. As you age beyond 40, your body demands higher levels of these compounds to counteract the effects of aging.

By naturally boosting NAD+ levels in your body, you revitalize your energy, mental clarity, metabolism, and immune function. This isn’t just about looking younger; it’s about feeling more energetic, vibrant, and youthful.

When you look in the mirror, you see a person who looks years younger and feels vibrant. In just 3 months, you smile and think, "Wow, this really works!" Why not allow yourself to relive this vibrant and youthful life again?

Three months from now, you wake up feeling refreshed and full of energy. Your skin has transformed, glowing with youthfulness, and those wrinkles have visibly softened.

Your eyes sparkle, and you can hardly believe the transformation.

As you move through your day, compliments start pouring in—people notice your vibrant energy and youthful appearance.

Friends and even strangers ask, "What's your secret?" At work, you handle tasks with a new level of sharpness, impressing everyone with your clear focus.

Soon enough, you become the center of attention for your positive outlook and increased productivity.

By the time you’re home, you have the energy to pursue hobbies, start a new fitness routine, or spend quality time with loved ones. Your metabolism feels revitalized, effortlessly helping you manage your weight. You notice your immune system is stronger, illnesses ease, and you recover quickly from any ailments.

In the past, you might have relied on traditional anti-aging solutions—vitamins, immunity supplements, creams, and collagen products—but they only offered temporary fixes, masking the symptoms without addressing the root causes of aging.

Now, you understand that the real solution lies in boosting the essential compounds you had in your youth.

As you age beyond 40, your body demands higher levels of these compounds to counteract the effects of aging. By naturally boosting NAD+ levels in your body, you revitalize your energy, mental clarity, metabolism, and immune function.

This isn’t just about looking younger; it’s about feeling more energetic, vibrant, and youthful.

Introducing NADrive: The Most Powerful and Safe NAD+ Supplement to Combat 15+ Signs of Aging, Restore Vitality, Improve Sleep, and Sharpen Mental Clarity

At HumaSpan, our mission has always been to enhance the quality of life by leveraging the latest breakthroughs in scientific research.

From the beginning, as founders, we’ve dedicated ourselves to understanding the aging process and have collaborated with leading experts in the field to bring you the most effective solutions.

Initially, we discovered that taking NAD+ directly in the form of pills or supplements was ineffective because the stomach’s heat destroys NAD+, rendering it useless.

👉🏿 Boost Your NAD/NMN Levels with the Purest, Most Potent Supplement ! 👉🏿

At HumaSpan, our mission has always been to enhance the quality of life by leveraging the latest breakthroughs in scientific research.

From the beginning, as founders, we’ve dedicated ourselves to understanding the aging process and have collaborated with leading experts in the field to bring you the most effective solutions.

Initially, we discovered that taking NAD+ directly in the form of pills or supplements was ineffective because the stomach’s heat destroys NAD+, rendering it useless. This realization led us to seek a better solution.

Harvard research revealed that a specific minimum dose of NMN (Nicotinamide Mononucleotide) is required to effectively boost NAD+ levels. Unlike direct NAD+ supplementation, NMN is a naturally occurring compound in all life forms and is a building block of NAD+.

Over time, studies have shown that NMN supplementation effectively boosts NAD+ levels. Because NMN is already present in our bodies and in some of the foods we eat, it’s recognized and safely metabolized by our system.

We found that most other supplements on the market sell low doses of NMN to reduce costs, making them ineffective.

This realization led us to seek a better solution.Harvard research revealed that a specific minimum dose of NMN (Nicotinamide Mononucleotide) is required to effectively boost NAD+ levels.

Unlike direct NAD+ supplementation, NMN is a naturally occurring compound in all life forms and is a building block of NAD+. Over time, studies have shown that NMN supplementation effectively boosts NAD+ levels.

Because NMN is already present in our bodies and in some of the foods we eat, it’s recognized and safely metabolized by our system. We found that most other supplements on the market sell low doses of NMN to reduce costs, making them ineffective.

Understanding this, we developed NADrive with the optimal dose—1000mg of NMN—to ensure that your NAD+ levels are replenished effectively.

By consistently maintaining high levels of NMN, you ensure that your NAD+ levels remain elevated as you age.

As NAD+ levels stay high, cellular regeneration and repair are enhanced, leading to increased energy, sharper focus, a boosted metabolism, better quality sleep, and a stronger immune system—all the key components of youthful vitality and a radiant glow.

After years of extensive research and rigorous testing, we developed NADrive, the most potent anti-aging supplement on the market.

Understanding this, we developed NADrive with the optimal dose—1000mg of NMN—to ensure that your NAD+ levels are replenished effectively.

By consistently maintaining high levels of NMN, you ensure that your NAD+ levels remain elevated as you age.

After years of extensive research and rigorous testing, we developed NADrive, the most potent anti-aging supplement on the market.

NADrive features a powerful blend of three ingredients: NMN, Bioperine, and Betaine Anhydrous. A common challenge with NMN has always been its bioavailability—how well your body can absorb and use it.

Even if taken in the right amount, NMN can be poorly absorbed. To address this, we added Bioperine, a natural compound that enhances nutrient absorption, ensuring that your body gets the maximum benefit from NMN.

We also included Betaine Anhydrous, a compound that hydrates cells, improves metabolic function, and boosts energy. This unique blend not only elevates NAD+ levels but also enhances overall cellular health, ensuring you get the most out of every dose.

Each batch is third-party tested to ensure quality and efficacy.

We also included Betaine Anhydrous, a compound that hydrates cells, improves metabolic function, and boosts energy.

This unique blend not only elevates NAD+ levels but also enhances overall cellular health, ensuring you get the most out of every dose. Each batch is third-party tested to ensure quality and efficacy.

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Our Story - How We Created NADrive

Research now shows that boosting NAD+ production can increase energy levels by over 400%. Imagine what that could mean for you! It’s like multiplying the energizing effects of coffee or energy drinks by ten—but without the crash.

This isn’t a jittery, artificial high; it’s a calm, steady, and long-lasting energy that feels fantastic throughout the day. By taking NMN supplements, you can maintain NAD+ levels akin to those you had in your 20s, allowing you to live with renewed vitality and energy promoting healthy longevity.

With NADrive, you’re not just addressing the symptoms of aging—you’re tackling its root cause, allowing your body to thrive at every stage of life.

Experience the Power of NADrive—Combat 15+ Signs of Aging, Restore Vitality, Improve Sleep, and Sharpen Mental Clarity

Backed By Extensive Research (Don't Just Take Our Word For It)

Studies suggest NMN supplementation can increase NAD+ levels in the body, potentially improving energy, metabolism and promoting cell repair

NMN shows promise in pre-clinical studies for various health benefits, particularly related to aging and age-related diseases

Betaine anhydrous shows potential for some health benefits, particularly related to homocysteine metabolism and liver health

Black pepper fruit extract (Bioperine) shows promise in enhancing nutrient absorption, offering potential benefits for overall health

If you have any questions or doubts, please feel free to contact our founders and experts at hello@humaspan.com. We'll respond within 24 hours.

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How To Use

If you have any questions or doubts, please feel free to contact our founders and experts at hello@humaspan.com. We'll respond within 24 hours.

FAQs

NAD+ is a coenzyme that plays a vital role in cellular functions, and can be found in every cell in the body. It has two primary functions; converting nutrients into energy, and regulating metabolic processes. Acting as an electron transporter, NAD+ facilitates various reactions and processes within our cells, working in tandem with NADH. It also regulates our sleep/wake cycle, or circadian rhythm.

NAD+ enables other molecules to perform their functions effectively, but as we age, levels of NAD+ decrease. This hinders the activities of various NAD (H) dependent enzymes in oxidative phosphorylation, TCA cycle, and glycolysis, resulting in lower ATP production. Additionally, it can affect levels of PARP and sirtuins, leading to the inactivation of certain downstream molecular pathways that play a role in DNA repair.

In other words, NAD+ is crucial for the proper functioning of the body, and its depletion can lead to a slower metabolic rate and less effective self-repair. Without NAD+, our cells will generate less energy, making it difficult for the body to carry out its functions. Therefore, the importance of NAD+ lies in its ability to help other beneficial molecules perform their jobs.

Exploring NMN and NAD+ for Mitigating Aging-Related Dysfunctions

Nicotinamide Mononucleotide (NMN) is the precursor of NAD+ that is naturally converted by the body into NAD+. NMN is more stable than NAD+ and increasing NMN levels has been shown to enhance NAD+ biosynthesis, which can help combat age-related dysfunctions.

Taking NMN is the optimal approach to increase NAD+ levels. NMN is more stable than NAD+ and can stably boost NAD+ pools for a longer duration. Increasing NMN has all the benefits of NAD+ and specifically helps with vision and hearing loss related to aging. Additionally, it promotes sirtuin genes, which activate longevity and anti-aging mechanisms.

There are only a few reliable suppliers of enzymatically produced NMN. Good quality NMN is highly-priced. One of the key things to look out for when choosing an NMN supplement is to choose 99.9% pharmaceutical-grade NMN from a reliable source. Another important factor in efficacy is proper dosing. In order for NMN or any supplement to be effective it must be properly dosed. There are plenty of underdosed supplements on the market. Infinium, NADrive and VitaSpan are meticulously dosed and formulated for optimal results.

Chronological age refers to the number of years you've been alive, while biological age is calculated based on physiological evidence of how old your cells and tissues are. Even if you are of a certain age, being healthy and fit can give you a lower biological age. On the other hand, if you lead a sedentary lifestyle or have chronic illnesses, your biological age may be higher than your chronological age. While chronological age is static and unchangeable, biological age can be influenced by lifestyle choices and supplementation.

Although there have been no human studies that specifically determine at what age one should start taking NAD+ supplements, current research recommends starting NAD+ supplementation around midlife, which could be as early as 30 years of age.

Taking NMN supplements daily can result in visible changes within two to three weeks, including increased energy and awareness. While the supplement starts working within fifteen minutes, the full benefits may not be physically noticeable until the two to three week mark. After consistent use, notable differences in both internal and external health may be observed.

You’ll immediately start to feel some of the short term benefits of NMN supplements within your first couple uses and they can consist of higher energy levels and also a greater awareness. After a few weeks of use, you should start to see some notable differences in how you look and feel, both internally and externally.

With the addition of NMN supplements to your daily routine, you may quickly feel a difference in your energy levels and metabolism. You may experience increased energy throughout the day and find it easier to remain active. This is the first indication that NMN is starting to work.

NMN requires time to activate its effects. It takes roughly three weeks for your body to acclimate to the supplement and begin absorbing the NMN molecules.

Around the 3-4 month mark, you should start to feel more profound effects. You will experience sustained and youthful energy, deeper and more restful sleep, and increased ability to focus. Additionally, some people will find it easier to recover from muscle soreness and bearable aching joints.

References

https://pubmed.ncbi.nlm.nih.gov/38102202/
https://sinclair.hms.harvard.edu/

Disclaimer: We are not endorsed or affiliated by Harvard, David Sinclair, NIH, WebMD, any of the articles, publications, or individuals mentioned on this website.